19 Sep Adult ADHD and Autism
Adult ADHD and Autism: Accurate Diagnosis and Treatment in NYC

Introduction: Why ADHD and Autism Are Often Missed or Misdiagnosed
Many successful adults come to me after years of therapy and psychiatric treatment for anxiety, depression, or burnout yet still feel something does not add up. Some were bright students who struggled with organization. Others had few friends as children but excelled academically. Many had seen multiple therapists and psychiatrists without clarity or resolution.
When I conduct an evaluation, I often uncover long-standing ADHD, autism, or both conditions. Often, people who I see were diagnosed with depression or social anxiety and treated with antidepressants. Proper diagnosis transforms treatment and, most importantly, quality of life.
This article explains how ADHD and autism overlap, differ, and are best diagnosed in adults. It also illustrates how careful, comprehensive assessments and individualized treatment lead to meaningful change.
Similarities and Differences in ADHD and Autism
Adults with ADHD and autism often share difficulties such as disorganization, strained social interactions, and high rates of anxiety or depression. Yet the conditions differ in important ways. ADHD is often marked by inattention, distractibility, impulsivity, inconsistent performance, and time blindness. Autism is more often defined by restricted interests, sensory sensitivities, rigidity in routines, and challenges with reciprocal social interaction.
Despite these distinctions, the overlap is significant. Both conditions can result in underachievement, strained relationships, and frustration despite intelligence and motivation. In fact, research has shown that about 20 to 30 percent of adults with ADHD also meet criteria for autism (Lai et al., 2019). This makes an accurate evaluation essential.
My Diagnostic Approach
Most of my patients come to me after standard checklists or short office visits have failed to capture the complexity of their history. My approach is designed to be more thorough and comprehensive. The complete assessment including speaking with the individual, testing, review past documents and assessments, and speaking with previous and current providers and family members can often take four to five hours. It can be very challenging to truly understand the person as a unique individual and not a diagnosis in order to provide a personalized and effective treatment plan.
The process begins with extended clinical interviews, often across several sessions, that cover childhood development, academic performance, and social history. I also use structured self-report measures such as the ASRS, CAARS, AQ, and RAADS-R, but I supplement them with customized questionnaires I have developed for my practice. This help identify subtle executive function challenges and interpersonal struggles that standard tools often miss.
Family input is a critical part of the evaluation. I frequently speak with parents or siblings and request childhood records, including grades, teacher reports, and in some cases early intervention plans (EIP), which provide valuable details about early learning and behavior.
To strengthen diagnostic accuracy, I use validated neuropsychological testing, particularly CANTAB (Cambridge Neuropsychological Test Automated Battery). CANTAB is widely regarded as a gold standard computerized assessment tool and has been validated in ADHD and autism research. Studies confirm that it can reliably identify executive function and memory deficits (Wild & Musser, 2014). This layered approach helps ensure accuracy and avoids the misdiagnoses that often persist for years. Also, often, it is vital to speak with previous therapists, specialists and psychiatrists to get past history and information.

Case Study 1: Charlie*, 49-Year-Old Financial Manager
Charlie* came to me after years of treatment for depression, anxiety, and social anxiety. He is a 49-year-old married, financial manager. He had worked with multiple therapists and psychiatrists but never felt fully understood. Professionally, he excelled at technical analysis at his financial firm but avoided leadership roles. Personally, he struggled in relationships and often felt isolated.
Through discussions with his parents, I learned of early difficulties with focus and friendships. Teacher reports from ages five and eleven documented inattention, fidgeting, and social withdrawal, and he had been placed in a special program for additional classroom support. CANTAB testing confirmed deficits in sustained attention and working memory.
The final diagnosis was combined-type ADHD with high-functioning autism. Treatment began with ADHD medication, carefully titrated to minimize side effects. Antidepressants and anti-anxiety medications that had been prescribed in the past were discontinued, as they were not addressing the root issue. Charlie also joined a social skills group designed for adults with ADHD and autism and worked with a dating coach and an autism-informed therapist.
Within a year, his work performance improved significantly, his confidence grew, and he built new friendships. Most importantly, he met a woman who had autism but not ADHD, and together they developed a thriving relationship based on mutual understanding.
Case Study 2: David*, Senior Tech Executive
David*, a senior manager at a global technology firm, had already been diagnosed with ADHD and prescribed medication. Despite this, he continued to struggle with procrastination, emotional regulation, and communication in high-stakes meetings.
During his evaluation, customized executive function questionnaires revealed persistent difficulties with task initiation and follow-through. CANTAB testing showed challenges with set-shifting and planning.
I implemented a treatment plan that combined Cognitive Behavioral Therapy focused on perfectionism and fear of failure with executive coaching that emphasized concrete productivity systems and accountability in team communication. Over time, David reduced procrastination, became more effective in delegation, and strengthened his leadership. Within months, he moved toward a higher executive role.
Case Study 3: Anna*, 42-Year-Old CEO
Anna*, the CEO of an international firm, came to me exhausted, anxious, and on the verge of burnout. She was intelligent and capable but often felt out of place in social situations and overwhelmed by sensory input.
Her childhood reports revealed no ADHD symptoms but early challenges with peer relationships. CANTAB confirmed intact attention but highlighted subtle deficits in emotion recognition. She also had a long history of masking her symptoms, a coping strategy especially common among women with autism.
The final diagnosis was autism spectrum disorder without ADHD. For Anna, medication was not required. Instead, treatment centered on autism-informed coaching, sensory management strategies in the workplace, and tailored support for navigating board dynamics and executive communication. With these changes, she built a sustainable leadership style, avoided burnout, and strengthened her executive presence.

Treatment Principles: Tailoring Care for Adults
The treatment of ADHD and autism in adults requires a tailored approach. For ADHD, evidence-based care often involves medication combined with Cognitive Behavioral Therapy, schema-focused therapy, and executive coaching. For autism, social skills groups, structured coaching, and workplace accommodations can make a significant difference. When ADHD and autism co-occur, the most effective strategies usually involve a combination of careful medication management and therapies that address both executive functioning and social cognition.
FAQs
Can ADHD and autism really occur together?
Yes. Research shows overlap in up to one-third of cases.
How do you distinguish between them?
The key is a comprehensive evaluation that includes developmental history, collateral family reports, neuropsychological testing, and a focus on whether difficulties arise more from attentional challenges or social reciprocity differences.
Why are women often missed?
Women are more likely to mask their symptoms, especially in autism, which can delay diagnosis.
What role does neuropsychological testing play?
Testing tools such as CANTAB provide objective measures of attention, planning, and flexibility that strengthen diagnostic accuracy.
Conclusion: Taking the Next Step
ADHD and autism in adults are often misunderstood, overlooked, or mistaken for anxiety and depression. Yet with a thorough evaluation, careful history gathering, validated tools, and nuanced clinical judgment, the right diagnosis can transform lives. Accurate assessment not only clarifies years of confusion but also opens the door to treatments that work — from personalized medication management to executive function coaching and autism-informed therapy.
I have seen professionals, executives, and leaders regain confidence, rebuild relationships, and achieve new levels of success once their challenges were properly understood. If you suspect you may be living with ADHD, autism, or both, know that clarity and effective support are possible.
As a Harvard-trained psychiatrist, I provide comprehensive diagnostic evaluations and integrative treatment plans designed for ambitious adults who want to thrive in their work and personal lives. The first step is simply reaching out.
References
Antshel, K. M., & Russo, N. (2019). Comorbidity of ADHD and autism spectrum disorder: Diagnostic and treatment challenges. Current Psychiatry Reports, 21(5), 34. https://doi.org/10.1007/s11920-019-1020-5
Kessler, R. C., Adler, L., Barkley, R., Biederman, J., Conners, C. K., Demler, O., Faraone, S. V., Greenhill, L. L., Howes, M. J., Secnik, K., Spencer, T., Ustun, T. B., Walters, E. E., & Zaslavsky, A. M. (2006). The prevalence and correlates of adult ADHD in the United States: Results from the National Comorbidity Survey Replication. American Journal of Psychiatry, 163(4), 716–723. https://doi.org/10.1176/ajp.2006.163.4.716
Lai, M. C., Kassee, C., Besney, R., Bonato, S., Hull, L., Mandy, W., Szatmari, P., & Ameis, S. H. (2019). Prevalence of co-occurring mental health diagnoses in the autism population: A systematic review and meta-analysis. The Lancet Psychiatry, 6(10), 819–829. https://doi.org/10.1016/S2215-0366(19)30289-5
Lever, A. G., & Geurts, H. M. (2016). DSM-5 criteria for autism spectrum disorder: Sensitivity and specificity in adults. Journal of Autism and Developmental Disorders, 46(8), 2743–2754. https://doi.org/10.1007/s10803-016-2816-2
Robbins, T. W., Gillan, C. M., Smith, D. G., de Wit, S., & Ersche, K. D. (2012). Neurocognitive endophenotypes of impulsivity and compulsivity: Towards dimensional psychiatry. Biological Psychiatry, 69(12), 1100–1108. https://doi.org/10.1016/j.biopsych.2010.12.021
Wild, K. V., & Musser, E. D. (2014). The Cambridge Neuropsychological Test Automated Battery in the assessment of executive functioning. In S. Goldstein & J. A. Naglieri (Eds.), Handbook of executive functioning (pp. 171–190). Springer Science + Business Media. https://link.springer.com/chapter/10.1007/978-1-4614-8106-5_11
About Dr. Scott Shapiro, MD

Scott Shapiro, MD is a Harvard-trained psychiatrist specializing in adult ADHD and a Performance and Productivity Executive Coach. He completed his residency at Massachusetts General Hospital and McLean Hospital, Harvard Medical School’s top teaching hospitals.
He practices in New York City and New Jersey, providing comprehensive assessments and treatment for executives, professionals, and leaders.
Website: www.scottshapiromd.com
Email: [email protected]
Phone: 212-631-8010
Disclaimer: Case examples are composites of real clinical experiences. Identifying details have been changed, and names are pseudonyms. All examples are used solely for educational purposes to illustrate the benefits of accurate diagnosis and treatment.
Craig Selinger
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